Stem Cell – Dr. Wade McKenna

3 Questions About Stemnexa

1. What is the biggest advantage of a Stemnexa-Rx™ treatment?

 

The biggest advantage of non-surgical Stemnexa procedure is, under the right circumstances, avoiding surgery.

The best example of this in the literature is with tennis elbow. It got that name because it was ruining tennis players’ careers. They couldn’t squeeze a racket or hit a backhand. Once this situation turns chronic it’s very difficult to treat. Even with surgical reconstruction, 20% of patients never return to normal.

Dr. McKenna – “We just published a case study about an Achilles’ tendon patient with a 10-year history of a chronic full thickness, intertendinous disruption that prevented her from playing tennis, shopping longer than 20 to 30 minutes or even walking on uneven terrain like cobblestone streets.

After one stem cell injection into the inner substance of her Achilles’ tendon, she was back playing tennis after 10 weeks, and at 7 months, she showed no signs of changes within the tendon on MRI. She had complete tendon homogeneity and was completely healed.”

In our practice, it’s common to for these patients to recover after STEMNEXA-Rx (non-surgical) without a splint or arm sling. They are typically doing stretches immediately after the injection. The day after that, they must ice their elbow. For the next several weeks, all they have to do is avoid heavy lifting, pushing or pulling. It’s common for these patients to regain normal function in 4 to 6 weeks.

 

 

2.  What are the biggest advantages of Stemnexa-Sx™ (Surgical)?

 

The latest technological advances are utilized at McKenna Orthopedics to try and correct the problem and shorten the healing time. This also affects the overall complication rate. The best example is a big surgery like an ACL reconstruction. The average healing time for ACL surgery is 369 days and during that time, patients are at increased risk of rupture and failure.

McKenna Orthopedics ACL patients have healed in as little as 16 to 20 weeks after Stemnexa-Sx. They have greatly reduced complication risk and can return to their normal activities much sooner.

Don’t rely on pain management to mask the injury. Explore biologic therapies with a group committed to the most minimally invasive procedures that help the body heal naturally and effectively.

Another big advantage is lower post-surgery infection rates. The normal infection rate for orthopedic surgeries is between 1% and 3%. After performing over 3,000 surgeries with biologics, Dr. McKenna has not had a single instance of post-surgery infection, which is quite remarkable.

The technology utilized in Stemnexa-Sx also reduces post-surgery inflammation, which increases patient comfort and speeds up the onset of the regenerative healing process.

Lastly, the proprietary technology enables Dr. McKenna to reconstruct tendons like the ACL using the largest, strongest tendon replacement without having to weaken another part of the patient’s body, which happens when doctors remove part of one tendon to repair another one.

3. Is Stemnexa FDA approved?

 

All of the Stemnexa Bone Marrow Procedures performed in the U.S. today are same-day procedures that are compliant with CFR 21 Part 1271, falling under the same surgery exemption discussed in 1271.15 (b).

Amniotic tissue, such as the tissue used in Stemnexa, has been used since 1910 in the US and is now FDA-exempt for treating wounds and other conditions. It was first used for treating eye problems, primarily corneas and is still widely used in ophthalmology today.

The Bio-Mac bone marrow aspiration cannula and the AUTOSPIN Magellan centrifuge have received 501(k) clearances from the US FDA.

 

Your Best Wrist Forward

Your Best Wrist Forward

 

Recently we have delved into the various functions of the body including the shoulder and the knee. The wrist, though a smaller part of the body, is intricate and in need of care and attention. The wrist is made up of several small bones, eight to be exact, known as carpals. Those bones support a tubal structure that runs through your wrist. That tube is called the carpal tunnel, and it has tendons and a nerve inside. It is covered by a ligament, which holds it in place.

Wrist pain is extremely common. Repetitive motion can damage your wrist. Typing, tennis, knitting can cause pain, or even carpal tunnel syndrome. Wrist pain that involves bruising and swelling can be a sign of injury. The signs of a possible fracture include misshapen joints and inability to move your wrist. Some wrist fractures are a result of osteoporosis.

Other common causes of wrist or hand pain are sprains and strains, tendonitis, arthritis, gout and pseudo-gout.

If you suffer from chronic or acute wrist or hand pain due to arthritis, bursitis, carpal tunnel syndrome or injury, then you may benefit from physical therapy, traditional orthopedic care, non-surgical stem cell injections or even stem cell-enhanced surgery.

At McKenna Orthopedics, we specialize in treating wrist discomfort, carpal tunnel syndrome, stem cell injections and surgery.

At McKenna Orthopedics we are augmenting BMAC with a proprietary, pliable tissue allograft (transplant) derived from human stem cells (donated from the amniotic tissue from a live birth), which functions as a biologic structural matrix to accelerate and enhance tissue healing and repair. It contains 108 different growth factors including more than 10 times the amount of WNT-4 and more than 60 times the amount of prostaglandin as competing products.

Prostaglandin inhibits inflammation, which occurs after injury and marks the beginning of the healing process. The faster we can tame this inflammation, the sooner the body can move on to the next phase of healing, regeneration.

To get in touch with Dr. McKenna, contact us at info@drwademckenna.com.

We’ve Got Your Back

The backbone is important. Sayings have derived over the years that include the notion of “the backbone” of the society, or “the backbone” the family. Why would this be? It’s probably because the backbone, also known as the spine is so important for the body to function.

 

Suffering doesn’t have to be a lifetime sentence. If you are dealing with chronic back pain from herniated or bulging disc, pinched nerve, or lumbar injury, we can step in and take the reigns. Here at McKenna Orthopedics, we have the expertise to get you healthy again. We know you are the backbone to someone, and we have the solutions to get you back to your best.

 

Traditional surgery may be the solution for you, depending on the severity of your injury or pain. Our board-certified surgeons have treated thousands of patients with excellent results. If going under the knife feels extreme, another option is using stem cell technology to help heal quickly, without the downtime of traditional surgery.

 

How can stem cells help my lower back pain?

A 2015 study published  in the scientific journal, Stem Cells, reported that patients suffering from chronic back pain due to degenerative disc disease who were treated by injections of their own bone marrow aspirate concentrate (BMAC) into the lumbar discs experienced noteworthy pain reduction one year after treatment.

 

Improvement in pain scores and impairment was demonstrated in 21 of 26 patients, with the most dramatic improvement in patients with higher CFU-F concentrations. Rehydration of the discs in eight of twenty patients according to MRI in conjunction with sustained pain relief through one year is promising for the use of this regenerative medicine approach.

 

At McKenna Orthopedics, we utilize tried and true techniques, but also incorporate new technologies, such as stem cell therapy, to bring our care to the next level. We strive to create healthy and beneficial results for our patients, because we know how important your mobilization is.

 

To schedule your appointment today, contact us at info@drwademckenna.com.

 

Ankles and Injuries: How We Can Help

Our bodies are fascinating, and so full of life, but sometimes injuries or age slows us down. Take our ankles. The ankle joins the foot and leg, and the inner bone, the tibia also known as the shinbone, supports most of the weight of your body. So you can say the ankle is pretty important for our mobility.

At McKenna Orthopedics, Dr. Wade McKenna has published a case study on CellR4 Repair, Replacement, Regeneration & Reprogramming on treating severe chronic Achilles tendon injury using bone marrow aspirate concentrate (BMAC), which contains several types of stem cells known to rebuild tissue. After ten weeks ultrasound-guided injections into the tendon, MRI imaging confirmed significant healing. At 32 weeks, MRI images showed that the tendon was almost completely healed.

The study focused on 27 patients that underwent surgery augmented with bone marrow aspirate concentrate (BMAC). Out of this group of patients 25 returned to their sport after six months post-treatment. Patients were walking without a boot in two months and were able to participate in light activity at around three months. This group of patients saw excellent results, which included no re-ruptures and early mobilization.

At McKenna Orthopedics, we are augmenting BMAC with a proprietary, pliable tissue allograft (transplant) derived from human placental amnion, which functions as a biologic structural matrix to facilitate and enhance tissue healing and repair. It contains 108 different growth factors including more than 10 times the amount of WNT-4 and more than 60 times the amount of prostaglandin as competing products.

Prostaglandin inhibits inflammation, which occurs after injury and marks the beginning of the healing process. The faster we can tame this inflammation, the sooner the body can move on to the next phase of healing, regeneration. WNT4 is arguably the single most important molecule required for wound healing.

To learn more or schedule your appointment, contact us info@drwademckenna.com.

 

You Need Your Knees

Did you ever know just how important your knees are? The knees act like a hinge, and provide steadiness and strength to support the entire body. That’s right, the entire body. Your knees serve as a critical function for standing, walking and running of course, and the fun-filled motions like dancing, jumping, twirling and turning.

When a knee (or knees) give out, it can affect your entire body, even your entire wellbeing. It may affect your ability to perform sports, or even basic functions like standing up from your favorite chair or walking outside to get the mail.

 

Knee replacement surgery is of course an option, and a really good option to get up and running (or walking) again. Dallas-based board certified orthopedic surgeon, Dr. Wade McKenna has performed over 20,000 surgeries, so he is more than qualified to make any repairs to your precious knees. But what if there was a quicker way to heal without a complete knee overhaul?

 

One of the breakthrough technologies that Dr. McKenna specializes in is called Stemnexa. Stemnexa combines a patient’s own bone marrow stem cells with amniotic tissue (donated from a mother after a live birth) to treat bone, muscle, tendon, ligament and cartilage injury in the knee. The amniotic tissue that Dr. McKenna uses in the procedure is composed of collagens and other proteins, which provide solution that supports both tissue growth and new collagen production during tissue regeneration and repair process. Though it sounds technical, the bottom line is that this procedure works, and patients have had amazing results from this relatively not invasive method.

 

Not sure what the next option is? We are here to help. If you are suffering with pain or discomfort, we would love to help ease your aches. If you are interested in either traditional surgery or learning more on how Stemnexa can benefit you, contact us today at info@drwademckenna.com. We are so excited to connect, and get to know you, and your knees better.

 

Knee replacement surgery

Needles or Knives? You Decide.

The cost of surgery goes beyond just the dollars and cents that come out of your pocketbook. Recovery time is a large price to pay when you go under the knife. But what if there was an easier and faster way to heal?

Enter stem cell therapy, Stemnexa. At McKenna Orthopedics, Dr. R. Wade McKenna leads the way to healing non-invasively. Pretty cool, huh?

So how exactly does it work?

Stem cell therapy may look a bit different for each application, but here is the gist.

  • We take human amniotic tissue (donated afterbirth from a mama who has delivered a live healthy baby) and utilize its components to inject the therapy where the patient is having problematic issues.
  • This cell therapy pumps oxygen to the tissue, reduces pesky inflammation all the while, preventing cell death. We want all the alive and well cells we can get, am I right?
  • The actual procedure takes less than your hour-long lunch break, and patients can potentially be on their feet in under a week.
  • Using the Stemnexa technology is the best way to heal quickly, and get back on your feet sooner than if you were to undergo traditional, under the knife surgery.

 

If you are interested or want to learn more about this super space-aged technology, fill out this easy questionnaire to see if you’re a candidate, and someone from our office will get back to you in a timely fashion. We are ready to make the connection, and we care about your health so you can live out your best life.

Still have questions? Feel free to send us a note, and we will be more than happy to get you in the right direction. You can also reach us at 940-627-6976. We understand how important it is to get back into your regular routines, so reach out today.

 

Stem cell procedure instead of knee surgery in Dallas, TX

Study on Compensated Rotator Cuff Tear Arthropathy by Orthopedic Surgeon and Stem Cell Specialist, Wade McKenna, DO Published in Techniques in Shoulder and Elbow Surgery

Study on Compensated Rotator Cuff Tear Arthropathy by Orthopedic Surgeon and Stem Cell Specialist, Wade McKenna, DO Published in Techniques in Shoulder and Elbow Surgery

Dallas-Fort Worth, Texas (PRWEB) November 08, 2015

A Study by orthopedic surgeon and stem cell specialist, Dr. Wade McKenna of the Riordan-McKenna Institute entitled, “Outpatient Treatment of Compensated Cuff Arthropathy Using Inlay Arthroplasty With Subscapularis Preservation” is published in the December edition of Techniques in Shoulder and Elbow Surgery.

Picture of Wade McKenna, DO

Dr. McKenna is co-founder and chief medical officer of the Riordan-McKenna Institute of Regenerative Orthopedics (RMI) in Southlake, Texas. Co-author of this work is Troy Chandler, PA-C from North Central Texas Orthopedics in Decatur, Texas.

Rotator cuff tear arthropathy sometimes develops in patients who have had a very large, long-standing rotator cuff injury. In CTA, changes in the shoulder due to the rotator cuff tear cause arthritis and lead to destruction of joint cartilage.

The Shoulder HemiCAP® restoration procedure is designed to match the shape and contour of individual patient’s cartilage and joint surface and be an ideal alternative to shoulder replacement. It simply recreates a smooth surface where the cartilage has worn away — similar to a filling for a tooth cavity.

The study examined a consecutive series of 50 CTA patients treated by Dr. McKenna from 2007 to 2015. It concluded that resurfacing the humeral head (shoulder bone) using a HemiCAP shoulder implant preserves the joint and avoids bone loss and complications associated with more invasive procedures like stemmed arthroplasty or total shoulder replacement.

Furthermore, the HemiCAP procedure disrupts the degenerative cycle of early-stage CTA, effectively addresses causes of pain, and avoids further muscle imbalance. The latter is achieved by a special deltoid muscle-splitting approach that leaves the tendon under the shoulder bone intact.

All of these advantages resulted in accelerated recovery and rehabilitation for patients.

“We are very pleased with the positive outcome of this study. Although we specialize in non-surgical stem cell interventions at RMI, sometimes, as in the case of CTA, surgical intervention is indicated. That’s why it’s important for patients to seek out an experienced orthopedic surgeon who, in addition to orthopedic expertise, is well versed on the latest advances in stem cell therapy. A surgeon needs both to know when stem cell therapy may be effective and when surgery, perhaps augmented with biologics like bone marrow aspirate concentrate (BMAC) and AlphaGEMS amniotic tissue product, is a better option,” commented Dr. McKenna.

About Riordan-McKenna Institute (RMI)

RMI specializes in non-surgical treatment of acute and chronic orthopedic conditions using *AlphaGEMS flowable amniotic tissue allograft and bone marrow aspirate concentrate (BMAC) that is harvested using the patented BioMAC bone marrow aspiration cannula. Common conditions treated include meniscal tears, ACL injuries, rotator cuff injuries, runner’s knee, tennis elbow, and joint pain due to degenerative conditions like osteoarthritis. RMI also uses AlphaPATCH amniotic membranes as part of a complete wound care treatment regimen.

RMI also augments orthopedic surgeries with BMAC and AlphaGEMS to promote better post-surgical outcomes.

BMAC contains a patient’s own mesenchymal stem cells (MSC,) hematopoietic stem cells (CD34+), growth factors and other progenitor cells. AlphaGEMS is composed of collagens and other structural proteins, which provide a biologic matrix that supports angiogenesis, tissue growth and new collagen during tissue regeneration and repair.

*AlphaGEMS and AlphaPATCH products are produced by Amniotic Therapies Inc. from donated amniotic tissue after normal healthy births. For more information about AlphaGEMS, please visit: http://www.rmiclinic.com/non-surgical-stem-cell-injections-joint-pain/stemnexa-protocol/

http://www.rmiclinic.com

801 E. Southlake Blvd.

Southlake, Texas

76092

Tel: (817) 776-8155

Toll Free: (877) 899-7836

Fax: (817) 776-8154

For the original version on PRWeb visit: http://www.prweb.com/releases/2015/11/prweb13068117.htm

Abstract: The role of “cell therapy” in osteonecrosis of the femoral head

The role of “cell therapy” in osteonecrosis of the femoral head.

Originally posted on July 17.

Abstract
Background and purpose – The value of core decrompression for treatment of osteonecrosis of the femoral head (ONFH) is unclear. We investigated by a literature review whether implantation of autologous bone marrow aspirate, containing high concentrations of pluripotent mesenchymal stem cells, into the core decompression track would improve the clinical and radiological results compared with the classical method of core decompression alone. The primary outcomes of interest were structural failure (collapse) of the femoral head and conversion to total hip replacement (THR). Patients and methods – All randomized and non-randomized control trials comparing simple core decompression with autologous bone marrow cell implantation into the femoral head for the treatment of ONFH were considered eligible for inclusion. The methodological quality of the studies included was assessed independently by 2 reviewers using the Cochrane Collaboration tool for assessing risk of bias in randomized studies. Of 496 relevant citations identified, 7 studies formed the basis of this review. Results – The pooled estimate of effect size for structural failure of the femoral head favored the cell therapy group, as, in this treatment group, the odds of progression of the femoral head to the collapse stage were reduced by a factor of 5 compared to the CD group (odds ratio (OR) = 0.2, 95% CI: 0.08-0.6; p = 0.02). The respective summarized estimate of effect size yielded halved odds for conversion to THR in the cell therapy group compared to CD group (OR = 0.6, 95% CI: 0.3-1.02; p = 0.06). Interpretation – Our findings suggest that implantation of autologous mesenchymal stem cells (MSCs) into the core decompression track, particularly when employed at early (pre-collapse) stages of ONFH, would improve the survivorship of femoral heads and reduce the need for hip arthroplasty.

 

Read Full Article.

Abstract on Stem Cell Research from AlphaMedPress

In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome

Originally posted on August 18

Abstract
: Mesenchymal stromal cells (MSCs) have been investigated as a treatment for various inflammatory diseases because of their immunomodulatory and reparative properties. However, many basic questions concerning their mechanisms of action after systemic infusion remain unanswered. We performed a detailed analysis of the immunomodulatory properties and proteomic profile of MSCs systemically administered to two patients with severe refractory acute respiratory distress syndrome (ARDS) on a compassionate use basis and attempted to correlate these with in vivo anti-inflammatory actions. Both patients received 2 × 106 cells per kilogram, and each subsequently improved with resolution of respiratory, hemodynamic, and multiorgan failure. In parallel, a decrease was seen in multiple pulmonary and systemic markers of inflammation, including epithelial apoptosis, alveolar-capillary fluid leakage, and proinflammatory cytokines, microRNAs, and chemokines. In vitro studies of the MSCs demonstrated a broad anti-inflammatory capacity, including suppression of T-cell responses and induction of regulatory phenotypes in T cells, monocytes, and neutrophils. Some of these in vitro potency assessments correlated with, and were relevant to, the observed in vivo actions. These experiences highlight both the mechanistic information that can be gained from clinical experience and the value of correlating in vitro potency assessments with clinical effects. The findings also suggest, but do not prove, a beneficial effect of lung protective strategies using adoptively transferred MSCs in ARDS. Appropriate randomized clinical trials are required to further assess any potential clinical efficacy and investigate the effects on in vivo inflammation.
SIGNIFICANCE:
This article describes the cases of two patients with severe refractory adult respiratory syndrome (ARDS) who failed to improve after both standard life support measures, including mechanical ventilation, and additional measures, including extracorporeal ventilation (i.e., in a heart-lung machine). Unlike acute forms of ARDS (such in the current NIH-sponsored study of mesenchymal stromal cells in ARDS), recovery does not generally occur in such patients.

Read Full Article.

UCLA Wide Receiver and Canadian Decathlon Standout Zack Bornstein Bounces Back After Stem Cell Therapy

UCLA Wide Receiver Zack Bornstein
UCLA Wide Receiver Zack Bornstein

UCLA wide receiver and Canadian decathlon standout Zach Bornstein suffered a hamstring tear 18 months ago. Conventional treatment and therapy were not working so Zach decided to undergo stem cell therapy at Riordan-McKenna Institute in late June 2015. Dr. McKenna treated Zack with precisely guided injections of bone marrow aspirate concentrate (BMAC) harvested with the patented BioMAC bone marrow aspiration cannula and *AlphGEMS amniotic tissue product.

Complete healing was confirmed by MRI 8 weeks after treatment:

1) No evidence for hamstring strain or denervation and no evidence for tendon tear.
2) No evidence for focal atrophy or hematoma.
3) No osseous abnormalities seen.

After receiving the MRI results, Zack’s father Dean said, “I am not a doctor but looks like you and your procedure has performed a medical miracle! …Thanks for all of your efforts.”

Zack is currently a red shirt freshman at UCLA. He played football at Oaks Christian High School from 2011-’14 and lettered 3 years in football and all 4 years in track. In 2013, Zack was named to the All-Marmonte 2nd team. He played in the FBU Youth All-American game in 2010. In track, he is considered to be one of the top decathletes in the country. Zack competed at the 2013 Pan American Junior Championships in Medellin, Columbia, finishing in 5th place with 7,097 points. In July of 2013, he became the Canadian Junior National Champion (6,918 pts). Zack won the silver medal at the 2013 Arcadia Invitational Decathlon, scoring 6,967 points to set a new California state record for juniors (2nd highest score in California state history). Zack is a 12-time National Champion, 44-time All-American and a member of three National Championship cross country teams.

*Amniotic tissue is donated after normal, healthy births.

 

Originally posted on RMI.